Fig. 5

The effect of insulin on the db/db mouse model. a The effect of insulin on the db/db mice away from the protein levels in the healthy db/+ mice. b Proteins with significant regulation in the db/db mouse model where insulin had an effect on the protein abundance towards the level in the healthy db/+ mice. There was no significant regulation in the STZ mouse model. Two-tailed Student’s t test was used for calculation of significance level when 2 groups were included and one-way ANOVA with Tukey post hoc test was used for the calculations including the db/db insulin group in the db/db mouse model. Graphs are shown with mean and 95 % CI and P < 0.05 is considered significant