Table 1 A partial list of novel proteins identified in retinoblastoma
From: Proteomic profiling of retinoblastoma by high resolution mass spectrometry
Gene symbol | Protein | Peptides | Fold change Tumor/normal |
|---|---|---|---|
HIST1H1B | Histone H1.5 | 6 | 16.9 |
CHGA | Chromogranin-A | 4 | 15.6 |
IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 | 2 | 13.1 |
KRT17 | Keratin, type I cytoskeletal 17 | 9 | 12.8 |
KRT16 | Keratin, type I cytoskeletal 16 | 17 | 12.8 |
LOC102723407 | Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like | 2 | 12.7 |
RACGAP1 | Rac GTPase-activating protein 1 | 1 | 12.3 |
SYK | Tyrosine-protein kinase SYK isoform Syk(S) | 2 | 12.1 |
KRT6C | Keratin, type II cytoskeletal 6C | 18 | 11.6 |
AHSG | Alpha-2-HS-glycoprotein | 9 | 11.3 |
CHAMP1 | Chromosome alignment-maintaining phosphoprotein 1 | 3 | 11.2 |
APOA2 | Apolipoprotein A-II | 3 | 10.9 |
DDX49 | Probable ATP-dependent RNA helicase DDX49 | 1 | 10.6 |
LAMA3 | Laminin subunit alpha-3 | 1 | 10.4 |
IGFALS | Insulin-like growth factor-binding protein complex acid labile subunit | 1 | 10.2 |
HMGA2 | High mobility group protein HMGI-C isoform a | 2 | 10.1 |
MCM4 | DNA replication licensing factor MCM4 | 16 | 10.0 |
KPNA2 | Importin subunit alpha-1 | 2 | 9.4 |
DDB2 | DNA damage-binding protein 2 | 1 | 9.4 |
IGF2BP3 | Insulin-like growth factor 2 mRNA-binding protein 3 | 7 | 9.3 |
MDK | Midkine isoform b | 1 | 9.0 |
APOA4 | Apolipoprotein A-IV | 14 | 8.5 |
IGLL5 | Immunoglobulin lambda-like polypeptide 5 | 5 | 8.4 |
MCM6 | DNA replication licensing factor MCM6 | 15 | 8.3 |