Fig. 4From: Fibrinogen alpha C chain 5.9 kDa fragment (FIC5.9), a biomarker for various pathological conditions, is produced in post-blood collection by fibrinolysis and coagulation factorsAnalysis of time course of FIC5.9 releasing with thrombin spiked/inhibited (a), plasmin spiked/inhibited (b), or neutrophil elastase inhibited (c) serum collection tubes. The relative amount of FIC5.9 was measured by FIC5.9 ELISA. Statistical comparison of silica-coated tube versus enzyme-spiked tube (asterisk), or inhibitor spiked tube (dagger symbol) was performed as described in the “Methods” sectionBack to article page