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Fig. 2 | Clinical Proteomics

Fig. 2

From: OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages

Fig. 2

Immunohistochemical staining results obtained for OLFM4. a Representative staining pictures for OLFM4 in diverticular disease tissues (DI and DH), adenoma low grade (ADN LG)/high grade (ADN HG) and adenocarcinoma (ADK) tissues (scale bar 100 µm). b Quantification summary for OLMF4. The relative percentage calculated over all the categories of signal (from “none” to “gradation”) are detailed in the table. The highest value obtained is underlined in colour in each patient group represented by histograms and significant differences were obtained between DH versus pTis (p < 0.05), DH versus pT1 (p < 0.001), DH versus pT2 (p < 0.001), ADN low grade versus pT2 (p < 0.01), DI versus pT2 (p < 0.05) and pT2 versus pT3 (p < 0.01). DH diverticulitis (adjacent normal tissue), DI diverticulitis inflammatory (diverticulitis zone itself), ADK adenocarcinome, ADN LG adenoma low grade, ADN HG adenoma high grade

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