Proteomics discovery set of patients | IHC characterisation set of patients | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Diverticular disease | Adenocarcinoma | Diverticular disease | Adenoma | Adenocarcinoma | |||||||
Healthy and paired inflammatory | pT1N0M0 | pT2N0M0 | Healthy and paired inflammatory | Low grade | High grade | pTis | pT1N0M0 | pT2N0M0 | pT3 | pT4 | |
Female n/male n (n total) | 9/11 (20) | 5/11 (16) | 10/10 (20) | 10/10 (20) | 10/10 (20) | 8/12 (20) | 5/7 (12) | 7/13 (20) | 7/13 (20) | 10/10 (20) | 10/10 (20) |
Age (years) median (range) | 63 (51–73) | 67 (52–87) | 78 (61–87) | 63 (41–84) | 64 (55–72) | 67 (48–92) | 60 (45–87) | 73 (54–91) | 70 (55–93) | 74 (54–42) | 75 (39–89) |
Localisation n | |||||||||||
Rectum | – | 2 | 7 | – | 5 | 5 | 1 | 4 | 2 | – | 1 |
Sigmoid | 18 | 2 | 2 | 18 | 4 | 5 | 8 | 8 | 10 | 5 | 4 |
Colon | 2 | 8 | 5 | 2 | 8 | 8 | 2 | 5 | 6 | 11 | 13 |
Cecum | – | 4 | 6 | – | 3 | 2 | 1 | 3 | 2 | 4 | 2 |
pN stage | – | – | – | NR | NR | NR | NR | NR | NR | 9 | 11 |
pM stage | – | – | – | NR | NR | NR | NR | NR | NR | 2 | 2 |
Percentage of tumoral cells mdian (range) | – | 60% (40–80) | 50% (10–80) | – | – | – | – | – | – | – | – |