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Table 1 Clinical information of patients included in the study

From: OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages

 

Proteomics discovery set of patients

IHC characterisation set of patients

Diverticular disease

Adenocarcinoma

Diverticular disease

Adenoma

Adenocarcinoma

Healthy and paired inflammatory

pT1N0M0

pT2N0M0

Healthy and paired inflammatory

Low grade

High grade

pTis

pT1N0M0

pT2N0M0

pT3

pT4

Female n/male n (n total)

9/11 (20)

5/11 (16)

10/10 (20)

10/10 (20)

10/10 (20)

8/12 (20)

5/7 (12)

7/13 (20)

7/13 (20)

10/10 (20)

10/10 (20)

Age (years) median (range)

63 (51–73)

67 (52–87)

78 (61–87)

63 (41–84)

64 (55–72)

67 (48–92)

60 (45–87)

73 (54–91)

70 (55–93)

74 (54–42)

75 (39–89)

Localisation n

 Rectum

2

7

5

5

1

4

2

1

 Sigmoid

18

2

2

18

4

5

8

8

10

5

4

 Colon

2

8

5

2

8

8

2

5

6

11

13

 Cecum

4

6

3

2

1

3

2

4

2

pN stage

NR

NR

NR

NR

NR

NR

9

11

pM stage

NR

NR

NR

NR

NR

NR

2

2

Percentage of tumoral cells mdian (range)

60% (40–80)

50% (10–80)

  1. The proteomic discovery patient set (n = 56) is detailed in the left panel and the immunohistology set of patients (n = 152) is provided in the right panel. Each patient with a diverticular disease provided paired tissue samples located in two different regions: diverticular disease healthy, DH (n = 20) and inflammatory, DI (n = 20)