Table 1 Representative list of proteins detected in the intraschisis fluid
From: Proteomic profiling of human intraschisis cavity fluid
Sl. no. | Protein symbol | Description | Clinical relevance |
|---|---|---|---|
1 | RDH14 | Retinol dehydrogenase 14 [Homo sapiens] | Visual cycle [16] |
2 | SGCE | Epsilon-sarcoglycan isoform 2 [Homo sapiens] | Myoclonus dystonia [46] |
3 | STK26 | Serine/threonine-protein kinase 26 isoform 2 [Homo sapiens] | – |
4 | TENM1 | Teneurin-1 isoform 3 [Homo sapiens] | – |
5 | ALMS1 | Alstrom syndrome protein 1 [Homo sapiens] | |
6 | ZFP90 | Zinc finger protein 90 homolog isoform 1 [Homo sapiens] | – |
7 | GRIN1 | Glutamate receptor ionotropic, NMDA 1 isoform GluN1-4a precursor [Homo sapiens] | Intellectual disability [49] |
8 | QSER1 | Glutamine and serine-rich protein 1 [Homo sapiens] | – |
9 | ESCO1 | N-acetyltransferase ESCO1 [Homo sapiens] | Bladder cancer [50] Endometrial cancer [51] |
10 | KIF4A | Chromosome-associated kinesin KIF4A [Homo sapiens] | – |
11 | MSC | Musculin [Homo sapiens] | – |
12 | TBC1D32 | Protein broad-minded [Homo sapiens] | – |
13 | SIGLEC7 | Sialic acid-binding Ig-like lectin 7 isoform 2 precursor [Homo sapiens] | – |
14 | PRICKLE4 | Prickle-like protein 4 [Homo sapiens] | Progressive myoclonus epilepsy-ataxia syndrome [52] |
15 | INSR | Insulin receptor isoform Short preproprotein [Homo sapiens] | Familial hyperinsulinemic hypoglycaemia [53] Rabson-Mendenhall syndrome [54] Leprechaunism [55] Non-insulin-dependent diabetes mellitus [56] Insulin-resistant diabetes mellitus with acanthosis nigricans [57] |
16 | HEPACAM | Hepatocyte cell adhesion molecule precursor [Homo sapiens] | Megalencephalic leukoencephalopathy with subcortal cysts [58] |
17 | KIAA1147 | Protein LCHN [Homo sapiens] | – |
18 | CAMSAP3 | Calmodulin-regulated spectrin-associated protein 3 isoform 1 [Homo sapiens] | – |
19 | CAPN1 | Calpain-1 catalytic subunit [Homo sapiens] | – |
20 | ANKRD24 | Ankyrin repeat domain-containing protein 24 [Homo sapiens] | – |