Table 4 Candidate proteins involved in the predominant canonical pathways that were identified in the intraschisis fluid
From: Proteomic profiling of human intraschisis cavity fluid
Pathway | p value | Number of candidate proteins | Protein symbols of candidate proteins detected in RS fluid |
|---|---|---|---|
LXR/RXR activation | 4.41E − 28 | 42/121 | A1BG, AGT, AHSG, ALB, AMBP, APOA1, APOA2, APOA4, APOB, APOC3, APOD, APOE, APOH, APOL1, APOM, C3, C9, C4A/C4B, CD14, CLU, FASN, FGA, GC, HPX, ITIH4, KNG1, LBP, LDLR, LYZ, ORM1, ORM2, PLTP, PON1, RBP4, S100A8, SAA4, SERPINA1, SERPINF1, SERPINF2, TF, TTR, VTN |
Acute phase response signalling | 1.43E − 27 | 48/168 | A2M, AGT, AHSG, ALB, AMBP, APOA1, APOA2, APOH, C2, C3, C5, C9, C1R, C1S, C4A/C4B, CFB, CP, CRABP1, F2, FGA, FGB, FGG, FN1, FTL, HP, HPX, HRG, ITIH2, ITIH3, ITIH4, KLKB1, LBP, ORM1, ORM2, PLG, RBP1, RBP3, RBP4, SAA4, SERPINA1, SERPINA3, SERPIND1, SERPINF1, SERPINF2, SERPING1, SOD2, TF, TTR |
Complement system | 1.11E − 23 | 23/36 | C2, C3, C5, C6, C7, C9, C1QA, C1QB, C1QC, C1R, C1S, C4A/C4B, C8A, C8B, C8G, CD59, CFB, CFD, CFH, CFI, ITGAM, MASP2, SERPING1 |