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Fig. 5 | Clinical Proteomics

Fig. 5

From: Downregulation of ATP1A1 promotes cancer development in renal cell carcinoma

Fig. 5

ATP1A1 overexpression induces the ROS generation (a) and cell apoptosis (b) in OS-RC-2 cells. Cells were harvested after transfection with pYR-ATP1A1 plasmids (ATP1A1) or the empty pYR vector (Control) in RCC cells for 48 h. a ROS generation was increased in OS-RC-2 cells. The experiment was performed in triplicate, *P < 0.01. b Cell apoptosis was detected by Annexin V-PI double staining and flow cytometry analysis. The experiment was performed in triplicate, *P < 0.05

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