Table 3 Membrane proteins of bEnd.3 identified in irradiated (R) and control (C) samples at 6, 24 and 48 h after irradiation, their average masses, average concentration on column (fmol) and number of replication in the MS runs; n = 6 (R); n = 6 (C)
Time point | Protein name | MW (Da) | Ave (fmol) in R | Protein replication | Ave (fmol) in C | Protein replication | Fold change (R:C) |
|---|---|---|---|---|---|---|---|
6Â h | PECAM-1 | 82,118.1 | 21.7 | 1 | 13.5 | 1 | 1.6 |
| Â | Cadherin 5 | 88,188.2 | 0.01 | 1 | 6.5 | 1 | 0 |
| Â | Annexin A2 | 38,961.4 | 6.4 | 1 | 6.7 | 1 | 1 |
| Â | Multimerin 2 | 105,833.7 | 0.01 | 1 | 6.5 | 1 | 0 |
| Â | Integrin beta 1 | 91,482 | 0.01 | 1 | 6.4 | 1 | 0 |
| Â | Ras related Rab-1B | 22,358.3 | 2.4 | 1 | 0.01 | 1 | 0 |
| Â | Protein lunapark | 47,785.1 | 13.2 | 1 | 0.01 | 1 | 0 |
24Â h | PECAM-1 | 82,118.1 | 67.9 | 5 | 52 | 5 | 1.2 |
| Â | Cadherin 5 | 88,188.2 | 49 | 6 | 16.4 | 6 | 3 |
| Â | Multimerin 2 | 105,833.7 | 25.4 | 3 | 28.9 | 3 | 0.8 |
| Â | Protein lunapark | 47,785.1 | 23.2 | 1 | 0.01 | 1 | 0 |
| Â | Endothelial protein C receptor | 27,668.3 | 7.2 | 1 | 0.01 | 1 | 0 |
| Â | Surface glycoprotein | 72,515 | 0.01 | 1 | 13.4 | 1 | 0 |
| Â | Annexin A2 | 38,961.4 | 9 | 1 | 9.4 | 1 | 1 |
| Â | Integrin beta 1 | 91,482 | 31.7 | 3 | 0.01 | 1 | 0 |
| Â | Fibroblast growth factor 8 | 23,891.9 | 19.8 | 1 | 0.01 | 1 | 0 |
48Â h | PECAM-1 | 82,118.1 | 55.4 | 5 | 36.7 | 3 | 1.5 |
| Â | Annexin A2 | 38,961.4 | 0.01 | 1 | 10.4 | 1 | 0 |
| Â | Cadherin 5 | 88,188.2 | 31.1 | 3 | 18.3 | 1 | 1.7 |
| Â | Multimerin 2 | 105,833.7 | 19.8 | 3 | 21.7 | 3 | 0.9 |
| Â | Cell surface glycoprotein | 72,515 | 15.8 | 1 | 0.01 | 1 | 0 |
| Â | Integrin beta 1 | 91,482 | 15.1 | 1 | 0.01 | 1 | 0 |
| Â | Ras related Rab 35 | 23,310.4 | 10.7 | 1 | 0.01 | 1 | 0 |
| Â | Fibroblast growth factor 8 | 30,647.8 | 0.01 | 1 | 4.9 | 1 | 0 |