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Table 3 Membrane proteins of bEnd.3 identified in irradiated (R) and control (C) samples at 6, 24 and 48 h after irradiation, their average masses, average concentration on column (fmol) and number of replication in the MS runs; n = 6 (R); n = 6 (C)

From: Identification of protein targets in cerebral endothelial cells for brain arteriovenous malformation (AVMs) molecular therapies

Time point Protein name MW (Da) Ave (fmol) in R Protein replication Ave (fmol) in C Protein replication Fold change (R:C)
6 h PECAM-1 82,118.1 21.7 1 13.5 1 1.6
  Cadherin 5 88,188.2 0.01 1 6.5 1 0
  Annexin A2 38,961.4 6.4 1 6.7 1 1
  Multimerin 2 105,833.7 0.01 1 6.5 1 0
  Integrin beta 1 91,482 0.01 1 6.4 1 0
  Ras related Rab-1B 22,358.3 2.4 1 0.01 1 0
  Protein lunapark 47,785.1 13.2 1 0.01 1 0
24 h PECAM-1 82,118.1 67.9 5 52 5 1.2
  Cadherin 5 88,188.2 49 6 16.4 6 3
  Multimerin 2 105,833.7 25.4 3 28.9 3 0.8
  Protein lunapark 47,785.1 23.2 1 0.01 1 0
  Endothelial protein C receptor 27,668.3 7.2 1 0.01 1 0
  Surface glycoprotein 72,515 0.01 1 13.4 1 0
  Annexin A2 38,961.4 9 1 9.4 1 1
  Integrin beta 1 91,482 31.7 3 0.01 1 0
  Fibroblast growth factor 8 23,891.9 19.8 1 0.01 1 0
48 h PECAM-1 82,118.1 55.4 5 36.7 3 1.5
  Annexin A2 38,961.4 0.01 1 10.4 1 0
  Cadherin 5 88,188.2 31.1 3 18.3 1 1.7
  Multimerin 2 105,833.7 19.8 3 21.7 3 0.9
  Cell surface glycoprotein 72,515 15.8 1 0.01 1 0
  Integrin beta 1 91,482 15.1 1 0.01 1 0
  Ras related Rab 35 23,310.4 10.7 1 0.01 1 0
  Fibroblast growth factor 8 30,647.8 0.01 1 4.9 1 0