Table 1 Clinical characteristics in discovery and validation set

Discovery set (LC–MS/MS)

 HC

4

4/0

30 ± 2

N/A

N/A

N/A

N/A

N/A

 MCD

4

1/3

49 ± 25

9.14 ± 3.6

1.2 ± 0.5

2.00 ± 0.31

2.1 ± 0.3

348 ± 88

 MN

4

2/2

50 ± 16*

6.56 ± 5.6

0.8 ± 0.2

1.00 ± 0.00

3.9 ± 0.4^†

172 ± 28^†

 FSGS

4

4/0

42 ± 23

6.17 ± 5.76

1.6 ± 0.4

2.67 ± 0.33

3.9 ± 0.4^†

240 ± 75

Validation set (ELISA)

 HC

8

4/4

36 ± 13

N/A

N/A

N/A

N/A

N/A

 IgAN

9

4/5

50 ± 10*

1.5 ± 1.1

0.98 ± 0.2

1.89 ± 0.20

4.0 ± 0.3^†

217 ± 33^†

 MCD

13

5/8

49 ± 19

7.69 ± 3.2^‡

1.0 ± 0.4

2.08 ± 0.18

2.5 ± 0.7

351 ± 81

 MN

26

16/10

55 ± 13*

6.13 ± 3.1^‡

0.98 ± 0.4

1.81 ± 0.15

3.2 ± 0.7^†,‡

239 ± 78^†

 FSGS

5

1/4

27 ± 15^{†, ‡, §}

6.26 ± 5.4^‡

1.94 ± 0.5^{†, ‡, §}

2.80 ± 0.20^{‡, §}

3.8 ± 0.5^†

249 ± 69^†