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Fig. 3 | Clinical Proteomics

Fig. 3

From: A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption

Fig. 3

Canonical pathway analysis, using Ingenuity Pathway Analysis, highlighted the key pathways represented by these plasma proteins, with the highest representation being the Liver X receptor (LXR)/retinoic X receptor (RXR) pathway. Top axis the percentage representation of proteins described in the respective canonical pathway. Bottom axis Statistical significance of the likelihood of pathway coverage (negative log of P value with Benjamini–Hochberg correction for multiple testing). Red fraction of bar: up regulated proteins; green fraction of bar: down regulated proteins; white fraction of bar: no overlap with dataset

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