Fig. 1
From: Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus
Specifically altered myosin:actin ratio in SLE-MPs. a Individual, raw β-actin intensity values as a function of myosin and other cytoskeletal protein intensities. Correlation coefficients (r2) and slopes (α) are given for the regression lines of the SLE-MPs (red) and the HC-MPs (HC, blue). In the SLE-MPs the slope of the lines for the myosin heavy chain (MYH9) and the myosin light chains are approximately twice the slopes found for the HC-MPs while no differences are observed for the α-actinin, α-actin-2, and actin-related protein. UniProt identifiers are included on the X-axes. b Intensity values of actin-normalized myosins, tubulins, and myosin light chain kinase in the SLE-MP and HC-MP cohort (red and blue symbols, respectively), medians (horizontal lines) and p values are indicated (Mann–Whitney, two-tailed)