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Fig. 3 | Clinical Proteomics

Fig. 3

From: Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus

Fig. 3

MP proteome profiling distinguishes SLE-MPs from HC-MPs. a Hierarchical clustering of SLE samples (red color above heat map) and HC samples (blue color) based on MP protein intensity data for a selection of 422 proteins that are significantly (q < 0.05) different between SLE and HC and with SLE/HC ratios ≥1.25 or ≤0.75. Heat map color code is based on the tiered color bar at the top of the plot going from 3 standard deviations below (green) to 3 standard deviations (red) above the mean value. b Receiver operating characteristics (ROC) curves for the ratio of α-enolase/cytochrome b-c1 complex subunit 2 (mitochondrial) (proteins marked with 1 and 2, respectively, in a) in the SSc–HC sample set (green, AUC = 0.54) and the SLE–HC sample set (red, AUC = 0.93)

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