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Fig. 4 | Clinical Proteomics

Fig. 4

From: Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus

Fig. 4

SLE-MP proteins and correlations with SLE disease activity indices (SLEDAI). a Levels of glycolytic enzymes in SLE samples from patients divided into two groups based on SLEDAI scores ≤4 (red symbols, low disease activity, n = 29) or above 4 (brown symbols, high disease activity, n = 15). Levels in the HC group are also shown. Except for a non-significant difference for glucose-6-phosphate dehydrogenase the glycolytic enzymes were increased significantly [*p < 0.05; **p < 0.01 (Mann–Whitney, two-tailed)] in the group with SLEDAI scores >4. b Correlation between protein intensities and SLEDAI scores for macrophage migration inhibitory factor (MIF, Spearman r = 0.37, p = 0.0156) and glutathione peroxidase 3 (GPX3, Spearman r = −0.52, p = 0.0005). Two SLE samples with zero MIF were removed from the sample set

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