Fig. 5
From: Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus
Increased levels of clearance proteins and proteins related to apoptosis in SLE-MPs. Intensities of specific clearance- (a) and apoptosis-related (b) proteins in HC (blue symbols) versus SLE-MPs (red symbols). Except for β2-glycoprotein 1 and CD47 (both significantly decreased) and annexin A1 (no difference), all proteins were significantly increased (Mann–Whitney, two-tailed) in the SLE-MP samples. Univariate p values and UniProt identifiers are indicated. Horizontal lines mark medians. c Levels of significantly increased granzyme A activated DNase/nm23-H1 and resulting ROC curve for SLE versus HC samples