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Table 6 Proteomic changes in the plasma of GHR−/− mice

From: The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies

Study design

Differentially expressed proteins (gene abbreviations)

GHR −/− Mice

Plasma proteomics of 6 male and female GHR−/− mice analyzed at 8, 16 and 24 months [160]

Increased

Decreased

APOA4

RBP-4

MBPC

APOE

HP

ALB

HBB

 

IL1β (females only)

MCP1 (females only)

APOA1 (age and isoform-specific increases and decreases)

  1. Proteomic changes in the plasma of the GHR knockout mouse, showing changes in several lipoproteins and decreases in inflammatory markers HP and MBPC, among others