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Table 2 Proteins that decreased in MSC in response to IFN-γ treatment

From: Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells

ID Gene Description Donor
4 69 74 140 150
(A)        
 Q9H6X2 ANTXR1 Anthrax toxin receptor 1 1.1 3.9 CTL 2.2 CTL
 Q8IZU8 DSEL Dermatan-sulfate epimerase-like protein CTL CTL CTL
 P17342 NPR3 Atrial natriuretic peptide receptor 3 5.2 1.3 CTL CTL CTL
 Q14123 PDE1C Calcium/calmodulin-dependent 3′,5′-cyclic nucleotide phosphodiesterase 1C 1.1 6.2 CTL CTL 2.1
 O00411 POLRMT DNA-directed RNA polymerase, mitochondrial CTL CTL 4.4 0.7 1.7
 Q13885 TUBB2A Tubulin beta-2A chain 6.5 11.6 6.4
 Q86Y38 XYLT1 Xylosyltransferase 1 3.0 CTL 3.4 CTL 1.3
(B)        
 Q9UPQ3 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 4.3 6.3 CTL 4.0 0.8
 Q9ULJ7 ANKRD50 Ankyrin repeat domain-containing protein 50 1.8 1.0 5.5 3.8 3.3
 Q6ZW76 ANKS3 Ankyrin repeat and SAM domain-containing protein 3 CTL CTL CTL 0.6 CTL
 Q8NCL9 APCDD1L Protein APCDD1-like CTL 2.4 CTL 1.9 3.0
 Q9BSF8 BTBD10 BTB/PoZ domain-containing protein 10 CTL CTL CTL CTL CTL
 Q8N5S9 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 CTL CTL 0.8 3.9 CTL
 P49674 CSNK1E Casein kinase I isoform epsilon 4.2 6.9 1.4 CTL 5.3
 Q9Y6M4 CSNK1G3 Casein kinase I isoform gamma-3 CTL CTL 1.1 CTL CTL
 P39880 CUX1 Homeobox protein cut-like 1 1.1 CTL CTL 13.7 CTL
 Q9H8V3 ECT2 Protein ECT2 CTL CTL 1.6 3.7 1.6
 O95864 FADS2 Fatty acid desaturase 2 8.3 4.2 4.5 2.2 1.7
 P02671 FGA Fibrinogen alpha chain CTL CTL 73.9 0.5 4.4
 P02679 FGG Fibrinogen gamma chain 18.9 CTL 42.8 0.4 3.0
 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 CTL CTL CTL CTL 4.0
 Q9Y2K7 KDM2A Lysine-specific demethylase 2A 5.4 0.3 1.1 CTL 6.4
 Q9BVG8 KIFC3 Kinesin-like protein KIFC3 5.2 CTL CTL 1.5 CTL
 Q659C4 LARP1B La-related protein 1B 3.5 CTL CTL CTL CTL
 Q15013 MAD2L1BP MAD2L1-binding protein CTL CTL CTL 0.7 CTL
 Q07864 POLE DNA polymerase epsilon catalytic subunit A CTL CTL 3.5 CTL 1.1
 Q9P2K3 RCOR3 REST Corepressor 3 CTL CTL CTL CTL CTL
 O15541 RNF113A RING finger protein 113A 1.2 1.2 CTL 18.5 4.8
 Q9GZN7 ROGDI Protein rogdi homolog CTL 0.0 CTL CTL 1.8
 Q99719 SEPT5 Septin-5 4.8 CTL CTL CTL 0.5
 O95359 TACC2 Transforming acidic coiled-coil-containing protein 2 CTL CTL CTL CTL CTL
 O15040 TECPR2 Tectonin beta-propeller repeat-containing protein 2 2.0 3.8 CTL 6.3 0.8
 Q9P273 TENM3 Teneurin-3 3.9 CTL 3.2 2.1 1.3
 Q86SZ2 TRAPPC6B Trafficking protein particle complex subunit 6B 0.3 CTL CTL CTL
 Q8IWR1 TRIM59 Tripartite motif-containing protein 59 CTL 3.2 4.0 CTL 0.9
 Q9NPG3 UBN1 Ubinuclein-1 CTL CTL CTL CTL CTL
 P62068 USP46 Ubiquitin carboxyl-terminal hydrolase 46 CTL CTL 1.5 CTL CTL
 Q5ST30 VARS2 Valine-tRNA ligase, mitochondrial CTL CTL 1.9 3.5 CTL
 Q9Y2K1 ZBTB1 Zinc finger and BTB domain-containing protein 1 0.5 CTL CTL 7.3 CTL
 Q9ULJ6 ZMIZ1 Zinc finger MIZ domain-containing protein 1 4.6 CTL CTL 1.6 CTL
  1. Proteins that were decreased following interferon treatment with transcripts that are (A) designated as IFN-γ responsive or (B) not designated as IFN-γ responsive. Results are presented as fold decrease following 20 h of IFN-γ treatment. IFN indicates only detected in interferon treated cells. CTL indicates only detected in untreated cells. – indicates not detected in indicated donor sample