Table 2 Capacity of plasma concentrations of SAA to distinguish between patients who went on to develop an infection and those who did not
Day | Number of patients | Mean SAA concentration (µg/mL) ± SD | ROC curve | ||||||
|---|---|---|---|---|---|---|---|---|---|
No infection | Infection | No infection | Infection | p value | AUC (95% CI) | Cut-off | SP% (95% CI) | SE% (95% CI) | |
pAUC (95% CI) | SP 90–100% (95% CI) | ||||||||
0 | 19 | 21 | 16 ± 38.4 | 61.8 ± 96.7 | 0.01 | 73.2 (55.9–87) | 14.2 | 84.2 (68.4–100) | 61.9 (38.1–81) |
2.53 (0–6.7) | 24.7 | 94.7 (84.2–100) | 42.9 (23.8–62.02) | ||||||
1 | 19 | 17 | 28.2 ± 62.6 | 57.7 ± 92.9 | 0.005 | 77.1 (60.1–92) | 8.8 | 63.2 (42.1–84.2) | 88.2 (70.6–100) |
2.3 (0.6–6.5) | 133.4 | 94.7 (84.2–100) | 35.3 (11.8–58.8) | ||||||
3 | 19 | 21 | 27.6 ± 55.2 | 140.9 ± 136 | 0.001 | 80.7 (66.2–93.2) | 21.4 | 84.2 (68.4–100) | 71.4 (52.4–90.5) |
3.6 (1.7–7.6) | 233.9 | 100 (100–100) | 33.3 (14.3–52.4) | ||||||
5 | 19 | 21 | 33.6 ± 66.4 | 137 ± 123.5 | 0.003 | 76.7 (61.2–89.7) | 87.8 | 94.7 (84.2–100) | 57.1 (38.1–76.2) |
3.5 (0.5–7.6) | 87.8 | 94.7 (84.2–100) | 57.1 (38.1–76.2) | ||||||