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Table 1 Clinical characteristics and MEST classification of included patients at time of biopsy

From: Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

 

Controls

IgAN without progression

IgAN with progression

N

15

16

9

Year of diagnosis

2000 ± 7.7

1996 ± 3.4

1998 ± 5.7

Proportion female

53.3%

12.5%

33.3%

Age (years)

32.0 ± 11.9

31.4 ± 13.4

31.2 ± 15.8

Serum creatinine (μmol/l)

79.3 ± 20.9

91.5 ± 21.5

105.8 ± 25.6*

Estimated glomerular filtration ratea (ml/min/1.73 m2)

113.13 ± 18.5

114.19 ± 25.3

91.89 ± 26.3*

Systolic blood pressure (mmHg)

118.6 ± 14.6

127.2 ± 14.3

135.4 ± 25.8

Diastolic blood pressure (mmHg)

77.6 ± 8.4

78.9 ± 11.6

78.8 ± 13.1

Urinary protein (g/24 h)

0.16 ± 0.17

1.76 ± 1*

2.00 ± 1.98*

Body weight (kg)

74.7 ± 11.9

76.1 ± 8.0

75.4 ± 12.5

No of years of follow-up

12.3 ± 7.7

16.3 ± 3.4

 

No of years from biopsy to ESRD

  

5.8 ± 2.5

 Percentage with M-score of 1

Not applicable

31.3%

44.4%

 Percentage with E-score of 1

Not applicable

31.3%

33.3%

 Percentage with S-score of 1

Not applicable

50%

77.8%

 Percentage with T-score of 1 or 2

Not applicable

0%

44.4%*

  1. p < 0.05 as compared to control. No variables were statistically significant between IgAN with versus without progression
  2. aEstimated by CKD-EPI equation