Fig. 2

Unsupervised hierarchical clustering of Proseek^® protein expression data. Unsupervised hierarchical clustering was based on mean-centered log2 transformed protein expression data of 92 Proseek^® Oncology Iv2 proteins (Correlation uncentered, average linkage) measured in the sera of 81 patients. Dark red indicates high levels of the protein relative to the average value, white indicates the average value, and dark blue indicates that the protein levels are below average (shown in the color bar on the right hand side). Color bar at the bottom indicates patient classification: healthy (green), benign (yellow), early stage ovarian cancer (red), and late stage ovarian cancer (black)