Table 2 The selected GO biological processes enriched in human plasma fibrin clots by STRING (version 10) bioinformatic tool
Pathway ID | Pathway description | Observed gene count | False discovery rate |
|---|---|---|---|
GO.0072376 | Protein activation cascade | 46 | 4.39E−61 |
GO.0042060 | Wound healing | 94 | 6.01E−53 |
GO.0007596 | Blood coagulation | 85 | 1.47E−52 |
GO.0009611 | Response to wounding | 95 | 1.32E−50 |
GO.0050878 | Regulation of body fluid levels | 90 | 8.85E−50 |
GO.0030168 | Platelet activation | 61 | 9.95E−50 |
GO.0002576 | Platelet degranulation | 43 | 1.88E−48 |
GO.0065008 | Regulation of biological quality | 167 | 1.44E−45 |
GO.0006950 | Response to stress | 173 | 8.05E−42 |
GO.0006956 | Complement activation | 30 | 2.20E−39 |
GO.0016192 | Vesicle-mediated transport | 91 | 1.54E−32 |
GO.0001775 | Cell activation | 69 | 5.21E−32 |
GO.0006887 | Exocytosis | 49 | 1.78E−30 |
GO.2000257 | Regulation of protein activation cascade | 20 | 8.87E−28 |
GO.0006959 | Humoral immune response | 33 | 1.54E−25 |
GO.0002376 | Immune system process | 101 | 1.83E−21 |
GO.0030193 | Regulation of blood coagulation | 24 | 5.05E−20 |
GO.0030195 | Negative regulation of blood coagulation | 19 | 4.06E−19 |
GO.0042730 | Fibrinolysis | 14 | 1.23E−17 |