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Table 4 The Distribution of the ≥ 510 gene symbols observed from the endogenous tryptic peptides of normal human plasma identified by X!TANDEM with respect to the human Gene Ontology (GO) Cellular Component as computed by STRING V10

From: The proteins cleaved by endogenous tryptic proteases in normal EDTA plasma by C18 collection of peptides for liquid chromatography micro electrospray ionization and tandem mass spectrometry

Term Number of genes p-value p-value_fdr p-value_bonferroni
Proteinaceous extracellular matrix 45 5.01E−24 7.94E−21 7.94E−21
Extracellular matrix 46 1.40E−22 1.11E−19 2.23E−19
Endoplasmic reticulum lumen 35 8.55E−22 4.51E−19 1.35E−18
Extracellular matrix component 28 3.25E−21 1.29E−18 5.15E−18
Collagen trimer 26 6.35E−21 2.01E−18 1.01E−17
Fibrillar collagen trimer 11 5.07E−17 1.34E−14 8.03E−14
Organelle lumen 153 2.79E−14 6.31E−12 4.42E−11
Intracellular organelle lumen 151 4.04E−14 8.00E−12 6.40E−11
Organelle part 220 5.07E−12 8.03E−10 8.03E−09
Basement membrane 16 3.64E−11 5.25E−09 5.77E−08
Intracellular organelle part 213 4.77E−11 6.30E−09 7.56E−08
Complex of collagen trimers 7 9.77E−11 1.19E−08 1.55E−07
Cytoplasm 255 1.75E−10 1.98E−08 2.78E−07
Organelle 277 1.33E−08 1.41E−06 2.11E−05
Endoplasmic reticulum part 51 3.26E−08 3.23E−06 5.17E−05
Intracellular organelle 259 4.64E−08 4.32E−06 7.35E−05
Intracellular 280 8.51E−08 7.49E−06 1.35E−04
Endoplasmic reticulum 62 1.59E−07 1.32E−05 2.52E−04
Cytoplasmic part 185 4.20E−07 3.33E−05 6.65E−04
Endomembrane system 108 4.90E−07 3.70E−05 7.76E−04
Intracellular part 276 5.95E−07 4.28E−05 9.42E−04
Membrane-bounded organelle 263 9.38E−07 6.46E−05 1.49E−03
Network-forming collagen trimer 4 1.25E−06 7.92E−05 1.98E−03
Collagen network 4 1.25E−06 7.92E−05 1.98E−03
Macromolecular complex 124 2.06E−06 1.25E−04 3.26E−03
Basement membrane collagen trimer 4 3.68E−06 2.16E−04 5.84E−03
Extracellular region part 112 5.58E−06 3.16E−04 8.85E−03
Protein complex 110 5.79E−06 3.16E−04 9.18E−03
Intracellular membrane-bounded organelle 238 6.50E−06 3.43E−04 1.03E−02
Collagen type V trimer 3 1.14E−05 5.81E−04 1.80E−02
  1. The headings are exactly as supplied by STRING. The Filtered (Filter 2) data can be found in Additional file 1, Additional file 2, Additional file 3, Additional file 4