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Table 8 Cellular Component from the filtered (best charge state best amino acid sequence) X!TANDEM and SEQUEST results where the difference between room temperature versus ice cold samples was at least fivefold or greater for 718 gene symbols

From: The proteins cleaved by endogenous tryptic proteases in normal EDTA plasma by C18 collection of peptides for liquid chromatography micro electrospray ionization and tandem mass spectrometry

Pathway ID Pathway description Count in gene set False discovery rate
GO:0005737 Cytoplasm 682 5.45E−19
GO:0044424 Intracellular part 795 8.65E−16
GO:0005622 Intracellular 800 2.61E−13
GO:0044444 Cytoplasmic part 506 3.57E−12
GO:0043229 Intracellular organelle 707 6.75E−12
GO:0043226 Organelle 750 1.63E−11
GO:0043231 Intracellular membrane-bounded organelle 664 1.79E−11
GO:0044422 Organelle part 523 8.31E−11
GO:0043227 Membrane-bounded organelle 716 9.14E−11
GO:0044446 Intracellular organelle part 509 4.29E−10
GO:0005623 Cell 841 1.37E−09
GO:0044464 Cell part 839 1.37E−09
GO:0012505 Endomembrane system 250 5.36E−05
GO:0005575 Cellular_component 883 6.89E−05
GO:0031090 Organelle membrane 217 6.89E−05
GO:0043233 Organelle lumen 281 0.00025
GO:0005634 Nucleus 429 0.000297
GO:0005829 Cytosol 227 0.000297
GO:0031974 Membrane-enclosed lumen 282 0.000446
GO:0043232 Intracellular non-membrane-bounded organelle 243 0.000538
GO:0070013 Intracellular organelle lumen 272 0.0011
GO:0016020 Membrane 516 0.00164
GO:0031988 Membrane-bounded vesicle 237 0.00164
GO:0098588 Bounding membrane of organelle 162 0.00272
GO:0016023 Cytoplasmic membrane-bounded vesicle 84 0.00325
GO:0031982 Vesicle 240 0.00413
GO:0005794 Golgi apparatus 107 0.0054
GO:0044428 Nuclear part 244 0.00708
GO:0031410 Cytoplasmic vesicle 88 0.00869
GO:0000139 Golgi membrane 55 0.0155
GO:0072562 Blood microparticle 16 0.0173
GO:0044431 Golgi apparatus part 67 0.02
GO:0031981 Nuclear lumen 222 0.0223
GO:0005759 Mitochondrial matrix 36 0.0233
GO:0043190 ATP-binding cassette (ABC) transporter complex 4 0.0278
GO:0070062 Extracellular exosome 188 0.0278
GO:0005783 Endoplasmic reticulum 113 0.0283
GO:0031838 Haptoglobin-hemoglobin complex 3 0.0293
GO:0032991 Macromolecular complex 283 0.0312
GO:0005730 Nucleolus 68 0.0368
GO:0044433 Cytoplasmic vesicle part 46 0.0415
GO:0012506 Vesicle membrane 38 0.0465
GO:0005654 Nucleoplasm 188 0.0478
  1. See the Additional file 1, Additional file 2, Additional file 3, Additional file 4 for the full list of proteins. The headings are exactly as supplied by STRING. The Filtered (Filter 2) data can be found in Additional file 1, Additional file 2, Additional file 3, Additional file 4