Fig. 3From: Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1Differential protein expression in vSCC variants. a Volcano plot showing the 282 of 2265 proteins that were significantly (p < 0.05) different by at least fourfold (red and blue dots) between Inf/FMX and Push/LPC, and those with a FDR < 20% (blue dots only). Significant proteins and FDRs were determined using the FDR method of Benjamini and Hochberg. p < 0.05 was considered significant and is reflected by a − log10 value of 1.3. b Hierarchical clustering of log2-transformed intensity values shows the distribution of the 282 significantly different proteins between the two variantsBack to article page