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Table 2 All up-regulated proteins in the HA-SA ST239 group

From: Distinct virulent network between healthcare- and community-associated Staphylococcus aureus based on proteomic analysis

Uniprot acc no. Prot description FC* (239/398) P value
Known virulence-related factors
D2NA85 FnbpA** 13.99 0.02
D2N8V1 Aerolysin/Leukocidin family protein 7.10 0.02
D2N8V0 Synergohymenotropic toxin 5.30 0.02
D2N3G2 SpA 3.26 0.03
D2NAS2 Cna 2.54 0.02
D2N627 Atl 2.46 0.02
D2N5J4 ClfA 2.11 0.02
Staphylococcal antigen
D2N9N2 SsaA 4.70 0.02
D2NAF1 IsaA 2.50 0.04
D2NAM0 IsaB 1.73 0.02
Other known proteins
D2N382 Penicillin-binding protein 3 (Pbp 3) (Pspb20) 69.88 0.02
D2N4Y0 Acetyl-CoA acetyltransferase 12.51 0.02
D2NAM6 N-acetylmuramoyl-l-alanine amidase 10.41 0.02
D2N4M0 N-acetylmuramoyl-l-alanine amidase Sle1 9.41 0.02
D2N5C6 LtaS 4.03 0.04
D2N9E7 HAD-superfamily hydrolase, subfamily IIB 3.87 0.02
D2N751 MsrA 3.75 0.02
D2NAT9 MnmE 3.74 0.02
D2N835 Universal stress protein family, putative 3.66 0.02
D2N6J2 Sun 3.51 0.04
D2N9E2 Morphine 6-dehydrogenase (Naloxone reductase) 3.46 0.02
D2NAH7 PanD 3.05 0.05
D2N655 YwbD 2.95 0.02
D2NAK8 Alkaline phosphatase 3 (Alkaline phosphataseIII) (APase III) 2.80 0.05
D2NAM5 Phage infection protein 2.77 0.02
D2N7Y0 RuvB 2.75 0.04
D2N917 Cardiolipin synthetase (Cardiolipin synthase) (CLsynthase) 2.58 0.01
D2N7V5 UPF0473 protein 2.58 0.02
D2N410 5 ~-nucleotidase, lipoprotein e (P4) family 2.47 0.04
D2N9P4 Inositol monophosphatase family protein 2.40 0.02
D2N6X6 Glycine betaine transporter OpuD 2.31 0.03
D2N6I0 PhnB 2.24 0.02
D2N953 Putative transcriptional regulator superfamily 2.10 0.02
D2N755 YphP 2.10 0.04
D2N5A8 NagA 2.10 0.03
D2N7I6 ScpB 1.97 0.04
D2N750 MsrB 1.94 0.05
D2N657 Phosphocarrier protein HPr 1.92 0.02
D2N6I4 RpoZ 1.84 0.04
D2N9L8 Butyryl-CoA dehydrogenase 1.84 0.02
D2N6L2 UPF0122 protein 1.81 0.04
D2N7K7 Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex 1.80 0.02
D2N6J3 RlmN 1.80 0.03
D2N681 Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase) 1.76 0.02
D2N5S9 AddA 1.73 0.02
D2N5P1 HAD-superfamily subfamily IIA hydrolase 1.69 0.03
D2N7P4 Superoxide dismutase 1.68 0.02
D2N7T3 RsfS 1.66 0.03
D2N842 Tpx 1.64 0.02
D2N7J2 Oxidoreductase 1.60 0.02
D2N941 UDP-N-acetylglucosamine 2-epimerase 1.60 0.02
D2N7L6 NusB 1.58 0.02
D2N6K8 AcpP 1.58 0.02
D2N4I9 HsdM 1.58 0.02
D2N4U4 RplJ 1.55 0.02
D2N6F6 MurD 1.54 0.02
D2N5D9 Ribonucleoside-diphosphate reductase, beta subunit 1.54 0.02
D2N8L2 Aminopeptidase PepS 1.54 0.03
Unknown proteins
D2N9M8 Uncharacterized protein 3.63 0.02
D2N5P0 Uncharacterized protein 2.49 0.04
D2N4W0 Uncharacterized protein 2.17 0.02
D2NA92 Uncharacterized protein 1.85 0.02
D2N685 Uncharacterized protein 1.62 0.04
D2N588 Uncharacterized protein 1.61 0.02
  1. *The calculation of FC (239/398) in this table is dividing the average value of peptide mass of proteins in ST239 strains by that average value in ST398 strains
  2. **Bold italics in this table is used to highlight the selected significantly differentially expressed genes for HA-SA ST239 up-regulated network construction