Fig. 1

Gene annotation enrichment analysis using the concept of GO annotations for poor responder (left column) and good responder (right column). Classification by the GO term biological process (BP) shows pathways and larger processes made up of the activities of multiple gene products, classification by the GO term cellular component (CC) shows where gene products are active and classification by the GO term molecular function (MF) shows molecular activities of gene products. Fold enrichment values for individual GO terms, count (genes involved in the term), p value and FDR (false discovery rate, calculated using the Benjamini–Hochberg procedure), listed next to the graph, were calculated using DAVID bioinformatics resources