Table 1 Significantly changed proteins from the individual samples evaluated by LMM
AC | Gene name | Protein names | Beta value | CI 95% (min–max) | FDR | Sig. peptides | Nr. peptides |
|---|---|---|---|---|---|---|---|
Increased | |||||||
P04040 | CATA | Catalase | 2.42 | (1.46–4.02) | 1 | 2 | |
P02766 | TTHY | Transthyretin | 1.38 | (1.02–1.86) | –f | 1 | 2 |
P15924 | DESP | Desmoplakin | 1.37 | (1.05–1.77) | 1 | 2 | |
A6NC86 | PINLY | Phospholipase A2 inhibitor | 1.35 | (1.09–1.66) | 1 | 1 | |
P80188 | NGAL | Neutrophil gelatinase-associated lipocalin | 1.35 | (1.02–1.78) | –f | 2 | 3 |
P18510 | IL1RN | Interleukin-1 receptor antagonist protein | 1.30 | (1.02–1.67) | –f | 1 | 1 |
Q8TDL5 | LPLC1 | BPI fold-containing family B member 1 | 1.29 | (1.03–1.61) | –f,f | 2 | 2 |
P0DJI8 | SAA1 | Serum amyloid A-1 protein | 1.28 | (1.00–1.62) | –f | 1 | 2 |
P01023 | A2MG | Alpha-2-macroglobulin | 1.26 | (1.10–1.45) | 1 | 4 | |
P02790 | HEMO | Hemopexin | 1.26 | (1.05–1.51) | 1 | 3 | |
Q08380 | LG3BP | Galectin-3-binding protein | 1.26 | (1.10–1.44) | 1 | 2 | |
P01834 | IGKC | Immunoglobulin kappa constant | 1.24 | (1.04–1.48) | 2 | 2 | |
P05155 | IC1 | Plasma protease C1 inhibitor | 1.23 | (1.02–1.50) | –f | 1 | 3 |
P08603 | CFAH | Complement factor H | 1.23 | (1.03–1.48) | 1 | 1 | |
P02760 | AMBP | Protein AMBP | 1.23 | (1.04–1.46) | 1 | 2 | |
Q92743 | HTRA1 | Serine protease HTRA1 | 1.23 | (1.10–1.37) | 1 | 2 | |
P22894 | MMP8 | Neutrophil collagenase | 1.22 | (1.08–1.38) | 1 | 1 | |
P07737 | PROF1 | Profilin-1 | 1.20 | (1.00–1.43) | –f | 1 | 1 |
P27169 | PON1 | Serum paraoxonase | 1.20 | (1.11–1.29) | 1 | 3 | |
P10909 | CLUS | Clusterin | 1.19 | (1.11–1.28) | 2 | 3 | |
Q96DA0 | ZG16B | Zymogen granule protein 16 homolog B | 1.18 | (1.03–1.37) | 1 | 1 | |
P04792 | HSPB1 | Heat shock protein beta-1 | 1.16 | (1.01–1.34) | –f | 1 | 2 |
Decreased | |||||||
P07602 | SAP | Prosaposin | 0.92 | (0.88–0.97) | 1 | 3 | |
Q9GZX6 | IL22 | Interleukin-22 | 0.88 | (0.79–0.99) | –f | 1 | 3 |
P01034 | CYTC | Cystatin-C | 0.88 | (0.79–0.97) | 1 | 1 | |
Q9Y624 | JAM1 | Junctional adhesion molecule A | 0.87 | (0.77–0.97) | 1 | 2 | |
Q13822 | ENPP2 | Ectonucleotide pyrophosphatase | 0.85 | (0.74–0.97) | 1 | 1 | |
O75223 | GGCT | Gamma-glutamylcyclotransferase | 0.82 | (0.73–0.93) | 1 | 3 | |
P37802 | TAGL2 | Transgelin-2 | 0.82 | (0.70–0.95) | 1 | 1 | |
Q14118 | DAG1 | Dystroglycan | 0.81 | (0.66–1.00) | –f | 1 | 2 |
P04080 | CYTB | Cystatin-B | 0.81 | (0.71–0.92) | 1 | 1 | |
P02751 | FINC | Fibronectin | 0.80 | (0.66–0.97) | 1 | 3 | |
P14780 | MMP9 | Matrix metalloproteinase-9 | 0.78 | (0.62–0.97) | –f | 2 | 3 |
P31944 | CASPE | Caspase-14 | 0.77 | (0.62–0.95) | 2 | 2 | |
P05164 | PERM | Myeloperoxidase | 0.75 | (0.62–0.92) | –f | 2 | 2 |
Q14019 | COTL1 | Coactosin-like protein | 0.72 | (0.58–0.89) | 1 | 2 | |
P06727 | APOA4 | Apolipoprotein A-IV | 0.71 | (0.54–0.93) | 1 | 3 | |
P01033 | TIMP1 | Metalloproteinase inhibitor 1 | 0.71 | (0.57–0.88) | 1 | 2 | |
O75594 | PGRP1 | Peptidoglycan recognition protein 1 | 0.70 | (0.54–0.90) | 3 | 3 | |
P29401 | TKT | Transketolase | 0.69 | (0.50–0.94) | 1 | 2 | |
P04406 | G3P | Glyceraldehyde-3-phosphate dehydrogenase | 0.68 | (0.57–0.81) | 1 | 1 | |
O75556 | SG2A1 | Mammaglobin-B | 0.67 | (0.47–0.96) | –f | 1 | 3 |
P02749 | APOH | Beta-2-glycoprotein 1 | 0.65 | (0.49–0.86) | –f | 2 | 2 |
P01008 | ANT3 | Antithrombin-III | 0.53 | (0.31–0.89) | 1 | 1 | |
Q6UWW0 | LCN15 | Lipocalin-15 | 0.43 | (0.25–0.72) | 1 | 2 | |
P08670 | VIME | Vimentin | 0.72 | (0.54–0.95) | 1 | 2 | |