Table 3 Intraclass correlation coefficient (ICC) and within- and between-subjects variability, of serum MALDI-TOF/MS peptidomic profiling calculated using different normalization strategies
| Â | ICC (median and IQR) | Within subjects variability (median and IQR) | Between-subjects variability (median and IQR) |
|---|---|---|---|
Non-normalized features | 0.58 (0.40–0.73) | 614.4 (192.2–19,560.0) | 771.6 (218.9–14,300.0) |
Median normalized features | 0.62 (0.49–0.73) | 0.04 (0.01–0.76) | 0.05 (0.01–1.02) |
sLMNLT features | 0.64 (0.49–0.72) | 0.76 (0.27–11.1) | 0.86 (0.27–18.6) |