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Table 4 Summary statistics of age, free prostate specific antigen (fPSA), total PSA (tPSA), free to total PSA (f/tPSA) and prostate cancer antigen 3 (PCA3) of the subjects included in the PCa study, grouped by the prostate biopsy histological results

From: MALDI-TOF peptidomic analysis of serum and post-prostatic massage urine specimens to identify prostate cancer biomarkers

 

N (%)

Age

mean ± SD

fPSA (μg/L)

Median

(IQR)

(n = 142)

tPSA (μg/L)

Median

(IQR)

(n = 142)

f/tPSA (μg/L)

Median

(IQR)

(n = 142)

PCA3 score

Median

(IQR)

(n = 142)

No alterations

57 (38.5%)

65.3 ± 6.7

0.74 (0.43–1.36)

5.05 (3.6–7.75)

15.7 (10.10–19.40)

23.50 (13.00–46.50)

BPH

7 (4.7%)

65.8 ± 8.3

1.50 (0.9–2.17)

7.01 (4.46–14.6)

17.00 (14.90–19.00)

49.00 (44.50–82.50)

Inflammation

12 (8.1%)

66.2 ± 4.3

0.47 (0.26––0.93)

4.00 (2.17–8.04)

11.00 (9.15–16.20)

22.00 (19.00–48.00)

AAH

2 (1.4%)

61.5 ± 0.7

0.47 (0.26–1.00)

7.13 (4.97–9.3)

6.45 (4.70–8.20)

21.50 (20.25–22.75)

ASAP

11 (7.4%)

64.7 ± 7.8

0.71 (0.48–1.10)

7.88 (3.85–9.16)

11.40 (9.60–15.70)

19.5 (14.5–32.00)

HGPIN

4 (2.7%)

69.0 ± 5.0

0.49 (0.25–1.35)

5.07 (4.11–5.83)

10.50 (6.30–22.40)

41.00 (26.00–70.00)

PCa

55 (37.2%)

66.8 ± 7.1

0.43 (0.27–0.83)

6.54 (4.08–9.23)

8.10 (5.30–11.13)

50.00 (24.00–88.00)

  1. No alteration, no histological alteration; BPH, benign prostatic hyperplasia; Inflammation, chronic inflammation; AAH, atypical adenomatous hyperplasia; ASAP, atypical small acinar proliferation; HGPIN, high-grade prostatic intraepithelial neoplasia; PCa, prostatic neoplasia