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Table 3 Lower abundant sperm proteins in normozoospermic samples that achieved pregnancy undergoing R-ICSI after IVF failure (n = 20)

From: iTRAQ-based analysis of sperm proteome from normozoospermic men achieving the rescue-ICSI pregnancy after the IVF failure

Swiss-Prot accession number

Protein name

Ratio (Mean ± SD) R-ICSI pregnancy/IVF pregnancy

P62937

Peptidyl-prolyl cis–trans isomerase A

0.76 ± 0.01

Q5VTE0

Putative elongation factor 1-alpha-like 3

0.76 ± 0.07

Q9BXU7

Ubiquitin carboxyl-terminal hydrolase 26

0.76 ± 0.08

Q9BS86

Zona pellucida-binding protein 1

0.75 ± 0.02

P02743

Serum amyloid P-component

0.75 ± 0.02

Q9UKU0

Long-chain-fatty-acid–CoA ligase 6

0.75 ± 0.16

Q8N4L4

Spermatid maturation protein 1

0.74 ± 0.03

Q8NEB7

Acrosin-binding protein

0.74 ± 0.09

Q13748

Tubulin alpha-3C/D chain

0.74 ± 0.04

P30101

Protein disulfide-isomerase A3

0.74 ± 0.05

P69905

Hemoglobin subunit alpha

0.72 ± 0.03

Q1ZYL8

Izumo sperm-egg fusion protein 4

0.71 ± 0.01

Q6NXR0

Interferon-inducible GTPase 5

0.70 ± 0.02

P07477

Trypsin-1

0.70 ± 0.10

P84085

ADP-ribosylation factor 5

0.68 ± 0.13

Q13642

Four and a half LIM domains protein 1

0.67 ± 0.05

Q499Z3

Schlafen-like protein 1

0.61 ± 0.06

P00352

Retinal dehydrogenase 1

0.61 ± 0.11

Q06830

Peroxiredoxin-1

0.60 ± 0.12

Q96C74

Ropporin-1-like protein

0.55 ± 0.07

  1. Annotations of altered proteins identified in sperm samples from the R-ICSI pregnancy group compared with the IVF pregnancy group. Values < 0.762 (P < 0.05) correspond to lower abundance in the R-ICSI pregnancy group. Standard deviation (SD)