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Fig. 1 | Clinical Proteomics

Fig. 1

From: Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes

Fig. 1

Gene expression in human BC tumors. Gene expression in ERα-positive BC, HER2-positive BC, and TNBC tumors are indicated in boxplots. Values are relative to normal breast tissue, with log2 Lowess normalized value > 0 indicating expression higher than and < 0 indicating expression lower than in normal tissue. Data are derived from The Cancer Genome Atlas (TCGA, https://cancergenome.nih.gov/). Indicated below each tumor subtype is the number of SCs identified by our proteomic analyses. Because TNBC SCs are derived from 3 cell lines, these values are sometimes presented as a range (panels b and c). ERα and HER2 (panels a and b, respectively) are provided for comparison. ***p < .001

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