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Fig. 7 | Clinical Proteomics

Fig. 7

From: Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy

Fig. 7

Comparative immunoblot analysis of normal wild type versus mdx-4cv liver extracts. Shown is a representative silver-stained SDS-PAGE gel and corresponding immunoblots with expanded views of labelling with antibodies to the fatty acid binding protein isoforms FABP1 and FABP5, as well as ferritin light chain, carbonic anhydrase isoform CA3, the voltage-dependent anion channel VDAC-1, the mitochondrial outer membrane protein translocation pore subunit TOM22, fibronectin and asporin. Lanes 1 and 2 represent total extracts from control wild type (wt) liver and mdx-4cv liver, respectively. Molecular mass standards (in kDa) are indicated at the left of the gel image. Graphical representations of the immuno-decoration levels of FABP1 and FABP5 are shown (Y-axis: % control): Student’s t test, unpaired; n = 4; *p < 0.05

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