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Table 2 Proteomic identification of liver proteins with a decreased abundance in the mdx-4cv model of dystrophinopathy

From: Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy

Accession

Gene name

Description

Unique peptides

Confidence score

Anova (p)

Max fold change

P09411

Pgk1

Phosphoglycerate kinase 1

4

13.9587

2.53E−09

14.97

Q64459

Cyp3a11

Cytochrome P450 3A11

5

17.1715

0.00056

9.53

P09813

Apoa2

Apolipoprotein A-II

2

9.5295

0.00130

6.98

P16045

Lgals1

Galectin-1

2

4.2800

0.00138

6.51

P47740

Aldh3a2

Fatty aldehyde dehydrogenase

7

24.1473

0.00055

6.02

P43883

Plin2

Perilipin-2

4

10.1732

0.02351

5.71

Q9DBE0

Csad

Cysteine sulfinic acid decarboxylase

13

41.5240

0.00220

5.63

P13745

Gsta1

Glutathione S-transferase A1

2

4.6699

0.02167

4.22

P01867

Igh-3

Ig gamma-2B chain C region

3

8.7297

0.01044

3.48

O55137

Acot1

Acyl-coenzyme A thioesterase 1

4

17.5564

0.00199

3.39

P29758

Oat

Ornithine aminotransferase, mitochondrial

22

74.8421

0.00012

2.79

Q9DBG5

Plin3

Perilipin-3

2

5.2382

0.01285

2.63

Q91VS7

Mgst1

Microsomal glutathione S-transferase 1

4

10.5855

0.00520

2.57

P06801

Me1

NADP-dependent malic enzyme

4

11.4988

0.01467

2.44

Q8VCH0

Acaa1b

3-ketoacyl-CoA thiolase B, peroxisomal

10

39.1412

0.00755

2.37

P22599

Serpina1b

Alpha-1-antitrypsin 1-2

3

7.0562

0.00500

2.34

Q9QZX7

Srr

Serine racemase

2

6.2347

0.02590

2.24

O54754

Aox1

Aldehyde oxidase 1

2

6.4066

0.00869

2.21

Q8BGT5

Gpt2

Alanine aminotransferase 2

8

26.9779

5.36E−05

2.17

Q8R086

Suox

Sulfite oxidase, mitochondrial

13

55.1200

0.00039

2.12

P16015

Ca3

Carbonic anhydrase 3

6

20.1812

0.00752

2.11

Q9D379

Ephx1

Epoxide hydrolase 1

3

8.8219

0.00583

2.11

P07759

Serpina3 k

Serine protease inhibitor A3 K

2

8.0261

0.00156

2.04

Q8VBT2

Sds

l-serine dehydratase/l-threonine deaminase

3

8.3410

0.04215

1.97

Q9QZD8

Slc25a10

Mitochondrial dicarboxylate carrier

6

22.5548

0.00119

1.94

Q91X83

Mat1a

S-adenosyl-methionine synthase isoform 1

7

21.4321

0.01511

1.92

Q9QXX4

Slc25a13

Calcium-binding mitochondrial carrier protein Aralar2

2

8.3671

0.02466

1.87

Q99L20

Gstt3

Glutathione S-transferase theta-3

6

23.9548

0.00840

1.86

Q8CAQ8-5

Immt

Isoform 5 of MIC complex subunit Mic60

4

11.5137

0.00397

1.86

Q922B1

Macrod1

O-acetyl-ADP-ribose deacetylase MACROD1

2

6.7757

0.00065

1.86

Q9D7I5

Lhpp

Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

3

8.5881

0.00382

1.85

Q921H8

Acaa1a

3-ketoacyl-CoA thiolase A, peroxisomal

2

8.07142

0.00063

1.84

Q64176

Ces1e

Carboxylesterase 1E

3

12.0204

0.01780

1.79

P61922

Abat

4-aminobutyrate aminotransferase, mitochondrial

7

24.4437

0.00016

1.75

O35490

Bhmt

Betaine–homocysteine S-methyltransferase 1

4

13.8152

0.03353

1.73

Q8BUV3

Gphn

Gephyrin

2

5.9008

0.01958

1.69

P02088

Hbb-b1

Hemoglobin subunit beta-1

2

7.9579

0.03523

1.67

P13707

Gpd1

Glycerol-3-phosphate dehydrogenase, cytoplasmic

9

30.8543

0.01008

1.63

Q91WG0

Ces2c

Acylcarnitine hydrolase

4

12.3891

0.00150

1.63

P15327

Bpgm

Bisphospho-glycerate mutase

3

10.8651

0.01946

1.61

P15626

Gstm2

Glutathione S-transferase Mu 2

3

8.9072

0.02081

1.60

Q9D0F9

Pgm1

Phosphogluco-mutase-1

2

7.4358

0.03949

1.60

Q99K51

Pls3

Plastin-3

3

15.7664

0.00796

1.58

Q9QXF8

Gnmt

Glycine N-methyltransferase

4

13.7679

0.00466

1.57

P41216

Acsl1

Long-chain-fatty-acid–CoA ligase 1

13

41.6748

0.00427

1.57

Q9DCM0

Ethe1

Persulfide dioxygenase ETHE1, mitochondrial

3

7.8214

7.48E−05

1.56

O35678

Mgll

Monoglyceride lipase

3

9.8837

0.00490

1.55

Q9WUZ9

Entpd5

Ectonucleoside triphosphate diphospho-hydrolase 5

2

6.6691

0.00680

1.55

Q9WVL0

Gstz1

Maleylacetoacetate isomerase

2

6.1377

0.00435

1.54

Q8CC88

Vwa8

von Willebrand factor A domain-containing protein 8

11

35.6611

0.00040

1.54

P34928

Apoc1

Apolipoprotein C-I

2

7.9163

0.00828

1.54

O08756

Hsd17b10

3-hydroxyacyl-CoA dehydrogenase 2

3

10.6184

0.00691

1.53

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Clinical Proteomics

ISSN: 1559-0275