Fig. 1
From: Ulcerative colitis: functional analysis of the in-depth proteome
Exploratory analysis. a Hierarchical clustering of the correlation coefficients of 6829 protein intensities (proteins quantified in at least 70% of the samples) after normalization shows a clear separation between ulcerative colitis (UC) and healthy controls. The two replicates (labeled with repl) show the highest correlations. b Multi-scatter plot of the averaged profiles for UC2, 3, 4, 6, 7, 11, 13, 14, and 16 (UC a), UC1, 5, 8, 9, 10, 12, 15, and 17 (UC b), H3, 4, 5, 6, 7, 8, 10, and 11 (H a), and H1, 2, 9, 12, 13, 14, and 15 (H b). The sample assignments to the groups a and b, respectively, are random. Blue numbers indicate Pearson correlation values. The averaged profiles show high correlations within the groups, and low correlations between the groups. c Principal component analysis (PCA) separates UC strongly from healthy controls in component 1 (39.9%)