Fig. 2
From: Proteomic analysis of plasma exosomes to differentiate malignant from benign pulmonary nodules
Exosomes extraction, identification and characterization. a Study design of present research. Samples were divided into 6 parts randomly before label-free mass spectrometry analyses: group1, group 2, group 3 for benign PNs and group1, group 2, group 3 for malignant PNs, each group including 3, 4, 3, 10, 10, 10 samples respectively. b Electron microscopy images of plasma exosomes, Bar = 100 nm. c CD9 and CD63 were detected in exsomes from 10 malignant PNs samples and 3 benign PNs samples by Western blotting. d Typical exosome proteins CD9, CD63, CD81, Syndecan and HSP70 were validated by mass spectrometry analyses