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Table 2 Differentially expressed proteins between malignant PNs group and benign PNs group

From: Proteomic analysis of plasma exosomes to differentiate malignant from benign pulmonary nodules

Protein symbol

p value

Fold (malignant/benign)

Peptide

Unique peptides

IGFALS

0.00053096

0.318426426

13

13

PLXDC1

0.00193538

0.389271884

10

10

ITIH1

0.012967236

0.272101082

13

1

APP

0.018235495

0.386848501

11

11

FGB

0.003852587

1.656288542

37

37

C16orf46

0.006916273

0.651005857

1

1

AZGP1

0.013813029

0.610964507

14

14

FGG

0.019121291

1.55572236

31

4

B4DPQ3

0.019588885

0.633906834

15

15

A8K0D8

0.022714839

0.524011735

16

16

ECM1

0.030964495

0.617536089

8

8

HP

0.041580346

0.610498412

27

12

NAPA

▲

▲

2

2

FLOT2

▲

▲

2

2

TPM1

▲

▲

15

1

NDRG4

▲

▲

1

1

ARPC5

▲

▲

1

1

DLD

▲

▲

2

2

MBL2

▲

▲

1

1

PSMA4

▲

▲

2

2

VDAC2

▲

▲

2

2

Q59FP5

*

*

6

4

FBN1

*

*

11

11

CSF1

*

*

2

1

CSPG3

*

*

3

3

KIF5B-ALK

*

*

1

1

IGKV2D-28

*

*

3

1

LAMB1

*

*

6

6

CD81

*

*

2

2

VASN

*

*

1

1

CFHR4

*

*

2

1

IL7R

*

*

5

5

HLA-B

*

*

12

0

  1. Asterisk “*” represents the detected protein in benign PNs group; Solid triangle “▲” represents the detected protein in malignant PNs group
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Clinical Proteomics

ISSN: 1559-0275