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Table 2 Association between cadmium in blood and circulating proteins in never smokers and results from replication in long term former smokers

From: Biomarkers of blood cadmium and incidence of cardiovascular events in non-smokers: results from a population-based proteomics study

Protein Never smokers (n = 1725) Long-term former smokers (n = 782)
Beta 95% L 95% H P Beta 95% L 95% H P
EGF − 0.37 − 0.65 − 0.09 0.010 − 0.04 − 0.50 0.41 0.852
HSP27 − 0.37 − 0.66 − 0.08 0.013 0.09 − 0.37 0.56 0.690
mAmP − 0.32 − 0.60 − 0.03 0.031     
GH − 0.27 − 0.51 − 0.03 0.028     
GDF15 0.25 0.01 0.50 0.047     
ST2 0.30 0.01 0.58 0.041     
TRAIL 0.32 0.02 0.61 0.036     
MMP12 0.32 0.06 0.57 0.017 0.56 0.17 0.95 0.005
SPON1 0.35 0.07 0.63 0.014 0.19 − 0.24 0.62 0.380
UPAR 0.36 0.09 0.62 0.009 0.44 0.04 0.83 0.031
KLK6 0.37 0.08 0.67 0.013 0.36 − 0.08 0.79 0.108
CCL3 0.38 0.10 0.66 0.009 0.43 0.01 0.85 0.044
TNFR1 0.38 0.09 0.67 0.010 0.37 − 0.06 0.80 0.087
CTSL1 0.39 0.10 0.67 0.008 0.57 0.15 0.99 0.008
CX3CL1 0.43 0.13 0.73 0.005 0.45 0.01 0.88 0.044
PAPPA 0.44 0.17 0.72 0.001 0.12 − 0.30 0.53 0.584
TNFR2 0.45 0.16 0.73 0.002 0.52 0.09 0.94 0.017
KIM-1 0.45 0.18 0.73 0.001 0.78 0.36 1.20 3.2 × 10−4
IL27A 0.46 0.17 0.75 0.002 0.38 − 0.05 0.80 0.082
FGF23 0.66 0.37 0.94 5.0 × 10−6 0.71 0.29 1.13 0.001
  1. 95% L and 95% H indicate confidence limits for Beta