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Table 3 Hazards ratio (HR) for incident CVD (n = 224, 13.1%) in 1705 never smokers, expressed per 1 SD increment of protein biomarkers

From: Biomarkers of blood cadmium and incidence of cardiovascular events in non-smokers: results from a population-based proteomics study

Protein Model 1a P Model 2b P
KIM-1 1.29 (1.12–1.48) < 0.001 1.16 (1.01–1.34) 0.033
FGF23 1.18 (1.03–1.36) 0.015 1.10 (0.96–1.27) 0.177
MMP12 1.29 (1.12–1.49) < 0.001 1.23 (1.06–1.43) 0.006
CTSL1 1.28 (1.11–1.47) 0.001 1.22 (1.05–1.41) 0.007
TNFR2 1.25 (1.09–1.44) 0.001 1.16 (1.01–1.34) 0.036
UPAR 1.32 (1.14–1.54) < 0.001 1.26 (1.08–1.47) 0.003
CCL3 1.15 (1.01–1.30) 0.037 1.06 (0.92–1.22) 0.441
CX3CL1 1.14 (1.01–1.30) 0.046 1.17 (1.02–1.33) 0.021
  1. aModel 1: adjusted for age and sex. Hazard ratios (95% confidence interval) in all models
  2. bModel 2: adjusted for age, sex, diabetes, systolic blood pressure, HDL, LDL, use of blood pressure, use of lipid-lowering drugs, and waist circumference