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Table 1 List of proteins correlating significantly with age and the associated biological functions

From: Age-associated changes in human tear proteome

Uniprot

Full name

Symbol

Ra

pb

Cell death

Cellular movement

Inflammatory/immune response

Viral infection

P80188

Neutrophil gelatinase-associated lipocalin

LCN2

0.36

0.011

x

x

x

x

P05109

Protein S100-A8

S100A8

0.40

0.004

x

x

x

x

P06702

Protein S100-A9

S100A9

0.36

0.013

x

x

x

x

P60709

Actin, cytoplasmic 1

ACTB

0.31

0.036

x

x

x

x

P02768

Serum albumin

ALB

0.35

0.013

x

x

x

x

P04083

Annexin A1

ANXA1

0.37

0.010

x

x

x

x

P07737

Profilin-1

PFN1

0.32

0.036

x

x

x

 

P06396

Gelsolin

GSN

0.32

0.036

x

x

  

P02787

Serotransferrin

TF

0.37

0.010

x

 

x

 

P63261

Actin, cytoplasmic 2

ACTG1

0.31

0.037

x

   

P22314

Ubiquitin-like modifier-activating enzyme 1

UBA1

− 0.32

0.036

x

   

P59665

Neutrophil defensin 1

DEFA1

0.40

0.004

 

x

x

 

P49788

Retinoic acid receptor responder protein 1

RARRES1

0.30

0.046

 

x

  

Q8NBJ4

Golgi membrane protein 1

GOLM1

− 0.31

0.036

   

x

Q13296

Mammaglobin-A

SCGB2A2

0.34

0.023

    

Q14002

Carcinoembryonic antigen-related cell adhesion molecule 7

CEACAM7

0.32

0.036

    
  1. aPearson’s product-moment correlation coefficient
  2. bBenjamini-Hochberg-adjusted p-value
  3. Expression based on 1 peptide only
  4. Proteins ACTB and ACTG1 are isoforms of the same protein