Table 2 Enriched diseases and biological functions filtered by activation z-score (absolute bias-corrected z-score > 1.5, p-value < 0.05) and ordered based on categories and sign of z-score
Categories | Diseases or functions annotation | Bias-corrected z-score | p |
|---|---|---|---|
Carbohydrate metabolism | Uptake of carbohydrate | 1.7 | 6.54E−04 |
Cardiovascular system development and function | Angiogenesis | 1.8 | 4.98E−05 |
Cell death and survival | Cell death of connective tissue cells | 2.0 | 6.98E−04 |
Cell-to-cell signaling and interaction | Response of granulocytes | 1.7 | 2.06E−06 |
Immune response of leukocytes | 1.7 | 2.60E−03 | |
Cellular function and maintenance | Internalization of cells | 1.7 | 3.18E−03 |
Engulfment of leukocytes | 1.6 | 3.29E−04 | |
Cellular movement | Cell movement of myeloid cells | 1.7 | 1.23E−05 |
Cell movement | 1.6 | 4.22E−07 | |
Chemotaxis | 1.6 | 1.15E−04 | |
Cell movement of neutrophils | 2.0 | 5.20E−05 | |
Chemotaxis of leukocytes | 1.7 | 5.48E−05 | |
Chemotaxis of neutrophils | 1.6 | 1.26E−03 | |
Inflammatory response | Inflammatory response | 1.7 | 1.68E−05 |
Organismal survival | Organismal death | 2.3 | 3.17E−05 |
Cell-to-cell signaling and interaction | Aggregation of cells | − 1.6 | 4.10E−05 |
Cell death and survival | Cell viability | − 1.8 | 3.63E−04 |
Cell survival | − 2.4 | 1.90E−06 | |
Cell death of kidney cell lines | − 2.4 | 2.15E−03 | |
Organismal development | Growth of organism | − 2.5 | 6.72E−05 |