Table 2 Fold change ratios of selected upregulated protein candidate biomarkers of IA, RA and PsA
Condition | Protein name | Gene name | Fold change ratio | p value | Adjusted p value |
|---|---|---|---|---|---|
IA | Stromelysin-1 | MMP3 | 24.01 | 2.00E−06 | 2.46E−05 |
Defensin alpha 3 | DEFA3 | 2.98 | 2.16E−02 | 4.97E−02 | |
Alpha-ketoglutarate-dependent dioxygenase | FTO | 1.70 | 9.62E−03 | 2.62E−02 | |
WASH complex subunit | FAM21C | 1.57 | 2.05E−04 | 1.06E−03 | |
T-box transcription factor | TBX3 | 1.54 | 1.26E−04 | 7.50E−04 | |
RA | Low affinity immunoglobulin gamma Fc region receptor | FCGR3A | 1.42 | 1.15E−02 | 4.06E−01 |
Coagulation factor XII | F12 | 1.40 | 4.33E−02 | 5.98E−01 | |
SPARC-like protein 1 | SPARCL1 | 1.36 | 1.47E−02 | 4.06E−01 | |
Rab GDP dissociation inhibitor beta | GDI2 | 1.25 | 1.47E−02 | 4.06E−01 | |
PsA | Periostin | POSTN | 1.72 | 2.32E−02 | 4.54E−01 |
Phosphoglycerate kinase 1 | PGK1 | 1.29 | 1.47E−02 | 4.06E−01 |