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Table 1 Regulated proteins of KG1a after co-culture with HS5 in over-represented KEGG pathways: NOD-like receptor signaling pathway and platelet activation

From: Screening differentially expressed proteins from co-cultured hematopoietic cells and bone marrow-derived stromal cells by quantitative proteomics (SILAC) method

KEGG pathway FDR
Protein accessions Gene names Protein descriptions Average ratio H/M
NOD-like receptor signalling pathway 1.67E−4 P07858 CTSB Cathepsin B 3.66
Q5XLA6 CARD17 Caspase recruitment domain-containing protein 17 2.91
P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 2.51
P45880 VDAC2 Voltage-dependent anion-selective channel protein 2 2.46
Q96PP8 GBP5 Guanylate-binding protein 5 2.38
P43490 NAMPT Nicotinamide phosphoribosyltransferase 1.89
Q96PP9 GBP4 Guanylate-binding protein 4 1.73
P32455 GBP1 Guanylate-binding protein 1 1.60
Platelet activation 1.5E−3 P43405 SYK Tyrosine-protein kinase SYK 0.61
Q01970 PLCB3 1-Phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 0.58
Q9BV40 VAMP8 Vesicle-associated membrane protein 8 0.56
Q7LDG7 RASGRP2 Calcium and DAG-regulated guanine nucleotide exchange factor I 0.56
P08754 GNAI3 Guanine nucleotide-binding protein G(k) subunit alpha 0.54
O00161 SNAP23 Synaptosomal-associated protein 23 0.49
P07948 LYN Tyrosine-protein kinase Lyn 0.30
  1. Columns list protein UniProt accession numbers, gene names, protein descriptions, and SILAC average ratios from two biological replicates