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Table 1 Clinical variables and demographic data from septic patients

From: Lipid metabolism impairment in patients with sepsis secondary to hospital acquired pneumonia, a proteomic analysis

 

Control (n = 23)

Sepsis (n = 27)

Survival (n = 8)

Non-survival (n = 19)

P valuea S × NS

Demographic data

     

Age, mean ± SD, year

65 ± 14.6

62.4 ± 12.8

60 ± 15.8

63.4 ± 11.6

0.5357

Sex (% of male)

60.9

70.4

87.5

63.2

0.3645

Place of acquired infection (%)

     

 Prior to ICU

NA

77.8

87.5

73.68

0.6334

 ICU acquired

NA

22.2

12.5

26.32

 

Severity of disease

     

Septic shock (%)

NA

77.8

87.5

73.68

0.6334

Severity scores, mean ± SD

     

 Apache II

NA

17.1 ± 6.5

15.6 ± 7.6

17.7 ± 6

0.4483

 SOFA

NA

8.3 ± 2.9

8.0 ± 2.9

8.4 ± 2.9

0.7709

 Delta-SOFA (D3-D0)

NA

(−) 0.4 ± 3.1

(−) 1.9 ± 3.4

0.7 ± 2.8

0.0666

Organ dysfunction (%)

     

 Cardiovascular

NA

88.9

87.5

89.5

1

 Renal

NA

37

37.5

36.8

1

 Respiratory

NA

85.2

75

89.5

0.5583

 Hematological

NA

11.1

0

15.8

0.5323

 Hepatological

NA

33.3

25

36.8

0.6758

 Central nervous system

NA

44.4

50

42

1

Underlying conditions

     

Chronic comorbidity (%)

     

 AIDS

NA

0

0

0

–

 COPD

NA

15.4

12.5

16.7

1

 Diabetes

NA

30.8

12.5

38.9

0.3602

 Chronic renal disease

NA

7.7

0

11.1

1

 Cardiovascular insufficiency

NA

11.5

0

16.7

0.5292

Drugs (%)

     

 Corticosteroids

NA

37

50

31.6

0.4147

  1. S survivor, NS non-survivor, NA not applicable, SOFA Sequential [Sepsis-related] Organ Failure Assessment, COPD chronic obstructive pulmonary disease
  2. aFisher’s exact test or unpaired t-test were applied to determine the P value when comparing survival and non-survival groups