Fig. 5
From: Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel
Western blotting and ELISA validation for 7 candidate early-stage CRC plasma protein biomarkers. a Validation of six biomarker candidates by Western blot and expression level of protein in plasma of all CRC stages (I–IV). b ADAMDEC1 ELISA on pooled and c individual patients. The bars indicate the means and SEMs. *p < 0.05, **p < 0.005, ***p < 0.0005 and ****p < 0.00005 calculated using unpaired t-test. CST3 cystatin-C, GPX3 glutathione peroxidase 3, CFD complement factor D, MRC1 macrophage mannose receptor 1, COMP cartilage oligomeric matrix protein, PON1 serum paraoxonase/arylesterase 1 and ADAMDEC1: ADAM-like decysin 1