Fig. 8

KEGG pathway enrichment analysis in case_vs_control group. The ordinate in the figure represents significantly enriched KEGG pathways. The abscissa represents the number of differentially expressed proteins contained in each KEGG pathway. As shown in the bar graph, color represents the significance of enriched KEGG pathways. Fisher’s exact test is used to calculate the p-value. Color gradient represents the size of P-value. The label at the top of the bar chart shows enrichment factor (richFactor ≤ 1), which represents the proportion of the number of differentially expressed proteins involved in a KEGG pathway to the number of proteins involved in this pathway among all identified proteins