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Table 2 STRING analysis of Biological Process of Gene Symbol distributions from the TRYP and TRYP STYP where delta and χ2 were both greater than 9 after correction

From: The plasma peptides of breast versus ovarian cancer

#Term IDTerm descriptionObserved gene countBackground gene countFalse discovery rate
O:0016043Cellular component organization55151634.00E−09
O:0071840Cellular component organization or biogenesis56753424.00E−09
O:0007017Microtubule-based process1066051.17E−08
O:0051641Cellular localization26721807.59E−08
O:0006996Organelle organization35631318.96E−08
O:0007010Cytoskeleton organization1399533.36E−07
O:0007018Microtubule-based movement572763.34E−06
O:0007399Nervous system development25722067.50E−06
O:0008104Protein localization23019663.52E−05
O:0120036Plasma membrane bounded cell projection organization13810343.52E−05
O:0048731System development42741444.68E−05
O:0033036Macromolecule localization25722684.69E−05
O:0070727Cellular macromolecule localization17113744.83E−05
O:0030030Cell projection organization14010674.96E−05
O:0034613Cellular protein localization16913677.45E−05
O:0009987Cellular process1271146520.00013
O:0051179Localization51652330.00015
O:0043170Macromolecule metabolic process70274530.00018
O:0007275Multicellular organism development47047260.00025
O:0032502Developmental process52854010.00025
O:0051649Establishment of localization in cell18916160.0003
O:0046907Intracellular transport16713900.00031
O:0090304Nucleic acid metabolic process39939410.00043
O:0051128Regulation of cellular component organization25223060.00047
O:0007156Homophilic cell adhesion via plasma membrane adhesion molecules341580.00063
O:0048856Anatomical structure development49650850.00066
O:0006139Nucleobase-containing compound metabolic process44945510.00082
O:0007155Cell adhesion1108430.00082
O:0006928Movement of cell or subcellular component16013550.001
O:0051276Chromosome organization1259990.001
O:0097435Supramolecular fiber organization603830.0012
O:0046483Heterocycle metabolic process45947160.002
O:0048666Neuron development997580.002
O:0000226Microtubule cytoskeleton organization603930.0022
O:0019219Regulation of nucleobase-containing compound metabolic process40841330.0022
O:0044260Cellular macromolecule metabolic process60264130.0022
O:0051130Positive regulation of cellular component organization13511280.0025
O:0006725Cellular aromatic compound metabolic process46047540.0028
O:0060255Regulation of macromolecule metabolic process57260720.0028
O:0098609Cell–cell adhesion624160.0028
O:0044085Cellular component biogenesis26725560.0029
O:0051252Regulation of RNA metabolic process38538900.0029
O:0010468Regulation of gene expression44045330.0033
O:0022607Cellular component assembly24723430.0034
O:0048699Generation of neurons16214220.0034
O:0071166Ribonucleoprotein complex localization271250.0034
O:0030182Neuron differentiation1159400.0038
O:0032989Cellular component morphogenesis937200.0038
O:0098742Cell–cell adhesion via plasma-membrane adhesion molecules402300.0038
O:0031175Neuron projection development826160.0043
O:0006611Protein export from nucleus291440.0048
O:0016070RNA metabolic process34234300.0048
O:0031323Regulation of cellular metabolic process56960820.0048
O:0050794Regulation of cellular process929104840.0048
O:1901360Organic cyclic compound metabolic process47449630.0049
O:0051168Nuclear export311610.005
O:0080090Regulation of primary metabolic process56059820.005
O:0051640Organelle localization775740.0051
O:0006403RNA localization372110.0053
O:0019222Regulation of metabolic process60465160.0053
O:0035023Regulation of Rho protein signal transduction271310.0053
O:2000112Regulation of cellular macromolecule biosynthetic process39540500.0053
O:0000902Cell morphogenesis826260.0054
O:0051171Regulation of nitrogen compound metabolic process54658270.0054
O:0071426Ribonucleoprotein complex export from nucleus261240.0054
O:0033043Regulation of organelle organization13411550.0058
O:0048468Cell development16614930.0058
O:0050658RNA transport341890.006
O:0006355Regulation of transcription, DNA-templated36036610.0061
O:0006405RNA export from nucleus271340.0061
O:0010467Gene expression36637330.0061
O:0022008Neurogenesis16815190.0061
O:0051056Regulation of small TPase mediated signal transduction483100.0061
O:0065007Biological regulation1026117400.0061
O:0003205Cardiac chamber development311660.0062
O:1903506Regulation of nucleic acid-templated transcription36136830.0068
O:0010556Regulation of macromolecule biosynthetic process40041430.0079
O:0006406mRNA export from nucleus231070.0083
O:0015833Peptide transport15714160.0084
O:0032501Multicellular organismal process59965070.0092
O:0051493Regulation of cytoskeleton organization654770.0092
  1. The protein–protein interaction statistics were: 485 nodes; 1148 edges; average node degree, 4.73; avg. local clustering coefficient, 0.325; expected number of edges: 851; PPI enrichment p-value: < 1.0e−16