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Table 2 An overview of downregulated proteins identified in Merkel cell carcinoma cell lines

From: Quantitative proteome analysis of Merkel cell carcinoma cell lines using SILAC

Cell lineUniProt entry nameProtein nameGene symbolRatio (H/L)
BroLiH10_HUMANHistone H1.0H1F00.45
MGAP_HUMANMAX gene-associated proteinMGA0.17
MKL-1ASXL1_HUMANPutative Polycomb group protein ASXL1ASXL10.48
TBB5_HUMANTubulin beta chainTUBB TUBB50.48
TAF2_HUMANTranscription initiation factor TFIID subunit 2TAF20.45
FBLN2_HUMANFibulin-2FBLN20.45
PRDX2_HUMANPeroxiredoxin-2PRDX20.44
SEPT5_HUMANSeptin-5Sep-050.44
FUS_HUMANRNA-binding protein FUSFUS0.44
BICD2_HUMANProtein bicaudal D homolog 2BICD20.43
SRRT_HUMANSerrate RNA effector molecule homologSRRT0.41
MAK_HUMANSerine/threonine-protein kinase MAKMAK0.40
CBX5_HUMANChromobox protein homolog 5CBX50.36
CHSP1_HUMANCalcium-regulated heat-stable protein 1CARHSP10.34
NUCB2_HUMANNucleobindin-2NUCB20.31
TPIS_HUMANTriosephosphate isomeraseTPI10.26
TRI13_HUMANE3 ubiquitin-protein ligase TRIM13TRIM130.22
L37A3_HUMANLeucine-rich repeat-containing protein 37A3LRRC37A30.08
CMGA_HUMANChromogranin-ACHGA0.03
KCTD9_HUMANBTB/POZ domain-containing protein KCTD9KCTD90.02
1433Z_HUMAN14-3-3 protein zeta/deltaYWHAZ0.02
MKL-2ALAT1_HUMANAlanine aminotransferase 1GPT0.49
GRP75_HUMANStress-70 protein, mitochondrialHSPA90.40
ULK2_HUMANSerine/threonine-protein kinase ULK2ULK20.34
NUCL_HUMANNucleolinNCL0.24
1433Z_HUMAN14-3-3 protein zeta/deltaYWHAZ0.04
PeTaKCTD9_HUMANBTB/POZ domain-containing protein KCTD9KCTD90.45
WaGaTMX1_HUMANThioredoxin-related transmembrane protein 1TMX10.39
RS30_HUMAN40S ribosomal protein S30FAU0.38
CPLX3_HUMANComplexin-3CPLX0.37
CA052_HUMANUPF0690 protein C1orf52C1orf520.27
RSMB_HUMANSmall nuclear ribonucleoprotein-associated proteins B and B’SNRPB0.23
RS28_HUMAN40S ribosomal protein S28RPS280.22
CQ047_HUMANUncharacterized protein C17orf47C17orf470.22
G3P_HUMANGlyceraldehyde-3-phosphate dehydrogenaseGAPDH0.21
GRP75_HUMANStress-70 protein, mitochondrialHSPA90.17
SAE2_HUMANSUMO-activating enzyme subunit 2UBA20.09
SRSF7_HUMANSerine/arginine-rich splicing factor 7SRSF70.06
MARCS_HUMANMyristoylated alanine-rich C-kinase substrateMARCKS0.05
MCC13WNK4_HUMANSerine/threonine-protein kinase WNK4WNK40.48
HNRPU_HUMANHeterogeneous nuclear ribonucleoprotein UHNRNPU0.44
RL18A_HUMAN60S ribosomal protein L18aRPL18A0.42
FUBP1_HUMANFar upstream element-binding protein 1FUBP10.27