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Table 1 Baseline characteristics of patients for validation

From: Urinary proteomics of Henoch-Schönlein purpura nephritis in children using liquid chromatography-tandem mass spectrometry

Characteristics

HSPN (n = 30)

Normal (n = 29)

HSP (n = 10)

Onset age (years)

9.4 ± 2.4

8.8 ± 2.9

9.3 ± 2.5

Male gender n (%)

20(66.7%)

12(41.4%)

6(60%)

Presenting symptoms n (%)

 Macro or microscopic hematuria

30(100%)

 Proteinuria

27(90%)

 Purpuric rash

30(100%)

10 (100%)

 Colicky pain

13(43.3%)

6(60%)

 Arthralgia

11(36.7%)

5(50%)

 Edema

 Bloody stools

Renal pathology n (%)

 IgA mesangial deposition

30(100%)

 Mesangial proliferation

30(100%)

 Crescents

15(50%)

 Segmental glomerulosclerosis

13(43.3%)

Laboratory measurements

 Serum IgA levels (g/l)

1.8 ± 0.5

1.9 ± 0.3

 Serum IgE levels (IU/ml)

193.3 ± 182.9

285.3 ± 106.7

 Serum creatinine (μmol/l)

36.0 ± 8.5

34.0 ± 5.4

 eGFR (ml/min/1.73 m2)

200.7 ± 31.3

203.8 ± 15.3

  1. eGFR is estimated by the Schwartz formula [K* height (cm)/serum creatinine (μmol/L)]
  2. HSPN Henoch-Schönlein purpura nephritis, Normal healthy controls, HSP Henoch-Schönlein purpura, eGFR estimated glomerular filtration rate