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Table 1 Detailed statistical analysis of 17 overlapping proteins

From: Identification of TUBB2A by quantitative proteomic analysis as a novel biomarker for the prediction of distant metastatic breast cancer

Protein name Dis-meta vs non dis-meta in pooled sample set Dis-meta vs non dis-meta in individual sample set High invasive vs low invasive in cell lines set Consistency of protein expression Fold-change > 1.2
t Test significance p Value Adjusted p value (BH FDR < 0.05) Fold-change t Test significance p Value Adjusted p value (BH FDR < 0.05) Fold-change t Test significance p Value Adjusted p value (BH FDR < 0.05) Fold-change
Glyceraldehyde-3-phosphate dehydrogenase + 0.01308 1 1.211 + 0.03681 1 1.260 + 0.01580 0.02242 0.815 N N
Tubulin beta-2A chain + 0.01730 1 1.219 + 0.01980 1 1.298 + 0.00076 0.00173 2.329 Y Y
Lactotransferrin + 0.00000 9.269E − 09 0.581 + 0.02619 1 0.546 + 0.00529 0.00866 0.551 Y Y
Stress-70 protein, mitochondrial + 0.00251 0.85696 1.114 + 0.04264 1 1.160 + 0.00003 0.00019 0.742 N N
Catenin alpha-1 + 0.04027 1 1.137 + 0.03017 1 1.189 + 0.00000 0.00003 0.473 N N
Bifunctional purine biosynthesis protein PURH + 0.03371 1 1.150 + 0.03078 1 1.180 + 0.00047 0.00119 0.710 N N
Heterogeneous nuclear ribonucleoprotein H + 0.04529 1 1.046 + 0.02779 1 1.111 N/D N/D N/D N/D N/D N
Isoform 2 of Multifunctional protein ADE2 + 0.01657 1 1.149 + 0.02412 1 1.147 + 0.00184 0.00355 0.742 N N
ADP/ATP translocase 3 + 0.01062 1 0.827 + 0.04718 1 0.833 + 0.00022 0.00068 1.416 N N
Exportin-5 + 0.00720 1 1.177 + 0.03871 1 1.227 + 0.00359 0.00619 0.868 N N
RNA-binding protein 39 + 0.04237 1 1.074 + 0.02435 1 1.119 + 0.00171 0.00334 0.916 N N
Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, isoform CRA_a + 0.04319 1 0.922 + 0.01636 1 0.834 + 0.00049 0.00124 0.889 Y N
Proteasome subunit beta type-4 + 0.00136 0.60958 1.111 + 0.03592 1 1.143 + 0.00066 0.00155 1.213 Y N
Beta-glucuronidase + 0.00266 0.83128 0.643 + 0.02986 1 0.630 N/D N/D N/D N/D N/D N
Mitotic checkpoint protein BUB3 + 0.00728 1 1.113 + 0.04702 1 1.112 + 0.03503 0.04592 1.057 Y N
Platelet-activating factor acetylhydrolase IB subunit gamma + 0.04161 1 1.221 + 0.02117 1 1.266 + 0.01903 0.02649 0.850 N N
2-hydroxyacyl-CoA lyase 1 + 0.01337 1 1.258 + 0.04677 1 1.314 + 0.00001 0.00010 0.575 N N
  1. (N/D-not detection, N-no, Y-yes)