Logistic regression analysis prioritizes CSF protein biomarkers that best classify AD. Logistic regression followed by ROC analysis for each of the 41 biomarkers alone was assessed. The top performing protein markers that classified AD from control (a) or AD from non-AD cases (b) are highlighted. c ROC curves for top performing proteins that predict classification of cases based on Aβ/Tau ratio. All protein AUCs are provided in Additional file 1: Table S9.